Williams E A, Evans T W, Goldstraw P
National Heart and Lung Institute, Royal Brompton Hospital, London, UK.
Thorax. 1996 Feb;51(2):114-6. doi: 10.1136/thx.51.2.114.
Further examination of the parameters of oxidative stress, perioperative changes in the vasoregulatory mechanisms of the pulmonary circulation, and characterisation of the endothelial insult that probably occurs in all patients undergoing lung resection is necessary if the operative conditions under which lung surgery is carried out are to be optimised. Perhaps, then, more insight might be gained into how to improve preservation of lungs for transplantation and how to protect the lung from significant injury following resection.
如果要优化肺手术的手术条件,就有必要进一步检查氧化应激参数、肺循环血管调节机制的围手术期变化,以及所有接受肺切除术的患者可能发生的内皮损伤特征。这样一来,或许就能更深入地了解如何改善供移植肺的保存,以及如何保护肺在切除后免受严重损伤。