Wilsher M L, Gurley A M
Department of Respiratory Medicine, Green Lane Hospital, Auckland, New Zealand.
Thorax. 1996 Feb;51(2):197-9. doi: 10.1136/thx.51.2.197.
Use of the flexible needle via the fibreoptic bronchoscope to aspirate mediastinal nodes or masses has largely superseded the use of the rigid needle via the rigid bronchoscope. However, the yield at fibreoptic bronchoscopy is relatively low, although this improves with the use of a wider gauge needle. In this study the sensitivity and the safety of rigid needle sampling of the mediastinum in the diagnosis of lung cancer is evaluated.
Transtracheal needle aspiration (TTNA) was performed with the rigid bronchoscope and a rigid aspiration needle under general anaesthesia using a previous computed tomographic (CT) scan as a guide to the sample site. A cytopathologist immediately examined the specimens for adequacy and preliminary diagnosis, thus determining the number of aspirations.
Twenty four patients were evaluated. The diagnostic sensitivity of TTNA was 88%. This led to a management decision in 21 patients. There were no false positives and no complications.
TTNA using the rigid bronchoscope with CT scanning and a cytopathologist present is a sensitive and safe way of diagnosing lung cancer in patients with a mediastinal mass or enlarged mediastinal nodes.
通过纤维支气管镜使用可弯曲针抽吸纵隔淋巴结或肿块在很大程度上已取代了通过硬支气管镜使用硬针的方法。然而,纤维支气管镜检查的阳性率相对较低,尽管使用更粗规格的针时这一情况会有所改善。本研究评估了硬针穿刺纵隔在肺癌诊断中的敏感性和安全性。
在全身麻醉下,使用硬支气管镜和硬穿刺针进行经气管针吸活检(TTNA),以先前的计算机断层扫描(CT)作为取样部位的指导。细胞病理学家立即检查标本是否足够并进行初步诊断,从而确定抽吸次数。
对24例患者进行了评估。TTNA的诊断敏感性为88%。这为21例患者做出了治疗决策。没有假阳性结果,也没有并发症。
在有纵隔肿块或纵隔淋巴结肿大的患者中,使用带有CT扫描且有细胞病理学家在场的硬支气管镜进行TTNA是一种敏感且安全的肺癌诊断方法。