Sano K, Nakaigawa N, Terashima K
Department of Urology, Kanagawa Children's Medical Center, Japan.
Hinyokika Kiyo. 1996 Feb;42(2):101-4.
Twenty-three cases of testicular tumor (10; malignant, 13; benign) in childhood are reported. The age at diagnosis was between 3 months old and 8 years old. Twelve patients visited the clinic within a month of first appearance of symptoms. All but one patient received high orchiectomy. One patient had resection of tumor because of its benign property. Eight of the 10 patients with malignancies received 30-50Gy of retroperitoneal radiation, including one patient (stage IIa) with retroperitoneal lymph node dissection. Two patients (stage I and IIa) with post-operative metastasis in lungs, brain and mediastinal lymph nodes were treated with chemotherapy repeatedly, but they died. Our latest therapy is; 1) high orchiectomy recommended for benign and stage I malignant testicular tumors in childhood, 2) retroperitoneal radiation and/or lymph node dissection limited for patients with stage II malignancy, and 3) Systemic chemotherapy for stage III malignant tumors. At least three years of follow up would be needed. Those who received radiation or chemotherapy should be followed longer.
报告了23例儿童睾丸肿瘤（10例恶性，13例良性）。诊断时的年龄在3个月至8岁之间。12名患者在症状首次出现后的一个月内就诊。除1名患者外，所有患者均接受了高位睾丸切除术。1名患者因肿瘤为良性而进行了肿瘤切除术。10例恶性肿瘤患者中有8例接受了30 - 50Gy的腹膜后放疗，其中1例（IIa期）患者进行了腹膜后淋巴结清扫。2例（I期和IIa期）术后出现肺、脑和纵隔淋巴结转移的患者接受了多次化疗，但均死亡。我们最新的治疗方法是：1）对于儿童良性和I期恶性睾丸肿瘤，建议进行高位睾丸切除术；2）对于II期恶性肿瘤患者，限制进行腹膜后放疗和/或淋巴结清扫；3）对于III期恶性肿瘤采用全身化疗。至少需要三年的随访。接受放疗或化疗的患者应随访更长时间。
