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心血管疾病预防的社区教育。明尼苏达心脏健康项目的发病率和死亡率结果。

Community education for cardiovascular disease prevention. Morbidity and mortality results from the Minnesota Heart Health Program.

作者信息

Luepker R V, Råstam L, Hannan P J, Murray D M, Gray C, Baker W L, Crow R, Jacobs D R, Pirie P L, Mascioli S R, Mittelmark M B, Blackburn H

机构信息

Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454-1015, USA.

出版信息

Am J Epidemiol. 1996 Aug 15;144(4):351-62. doi: 10.1093/oxfordjournals.aje.a008936.

Abstract

The Minnesota Heart Health Program was a community trial of cardiovascular disease prevention methods that was conducted from 1980 to 1990 in three Upper Midwestern communities with three matched comparison communities. A 5- to 6-year intervention program used community-wide and individual health education in an attempt to decrease population risk. A major hypothesis was that the incidence of validated fatal and nonfatal coronary heart disease and stroke in 30- to 74-year-old men and women would decline differentially in the education communities after the health promotion program was introduced. This hypothesis was investigated using mixed-model regression. The intervention effect was modeled as a series of annual departures from a linear secular trend after a 2-year lag from the start of the intervention program. In the education communities, 2,394 cases of coronary heart disease and 818 cases of stroke occurred, with 2,526 and 739 cases, respectively, being seen in the comparison communities. The overall decline in coronary heart disease incidence was 1.8 percent per year in men (p = 0.03) and 3.6 percent per year in women (p = 0.007). For stroke, there were no significant secular trends. The authors recently published findings showing minimal effects of sustained intervention on risk factor levels. In the current report, there was no evidence of a significant intervention effect on morbidity or mortality, either for coronary heart disease or for stroke.

摘要

明尼苏达心脏健康项目是一项关于心血管疾病预防方法的社区试验,于1980年至1990年在中西部上游地区的三个社区以及三个匹配的对照社区开展。一项为期5至6年的干预项目采用了社区层面和个人健康教育,试图降低人群风险。一个主要假设是,在引入健康促进项目后,30至74岁男性和女性中经证实的致命和非致命冠心病及中风的发病率在接受教育的社区中会有不同程度的下降。该假设通过混合模型回归进行研究。干预效果被建模为从干预项目开始起滞后2年后偏离线性长期趋势的一系列年度偏差。在接受教育的社区中,发生了2394例冠心病病例和818例中风病例,对照社区分别为2526例和739例。男性冠心病发病率的总体下降幅度为每年1.8%(p = 0.03),女性为每年3.6%(p = 0.007)。对于中风,没有显著的长期趋势。作者最近发表的研究结果显示,持续干预对风险因素水平的影响微乎其微。在本报告中,没有证据表明干预对冠心病或中风的发病率或死亡率有显著影响。

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