Tan L C, Sutton G L, Taffinder N J, Perry M, Fail T
Department of Surgery, Queen Alexandra Hospital, Cosham, Portsmouth.
Ann R Coll Surg Engl. 1996 Jul;78(4):340-4.
Carotid endarterectomy has been established by two large randomised controlled trials (European Carotid Surgery Trial (ECST) and North American Symptomatic Carotid Endarterectomy Trial (NASCET)) as an important surgical procedure for the prevention of ischaemic strokes in patients presenting with transient cerebral ischaemia or non-disabling strokes attributable to severe ipsilateral carotid artery stenosis. The operation carries significant risk of death and stroke and it has been advocated by some that carotid endarterectomy should only be performed in a small number of designated regional centres in order to achieve good surgical results. It is doubtful that the regional centres alone can cope with the increasing numbers of patients requiring carotid endarterectomy and there is therefore a requirement for the procedure to be carried out by vascular surgeons in district general hospitals. It is important that surgical results are audited to ensure that comparable outcomes are achieved. We present an audit of our experience of carotid endarterectomy since 1981. A total of 149 consecutive carotid endarterectomies were performed by a single surgeon with a special interest in carotid surgery. The results are comparable to ECST with a 30-day mortality of 0% and an overall 30-day stroke rate of 5.7% (major strokes) for patients with severe, ie 70-99%, ipsilateral carotid artery stenoses. We have shown that carotid endarterectomy is an operation that can be performed safely and with good results by suitably trained surgeons in district general hospitals.
两项大型随机对照试验(欧洲颈动脉外科试验(ECST)和北美症状性颈动脉内膜切除术试验(NASCET))已证实,颈动脉内膜切除术是预防短暂性脑缺血或由严重同侧颈动脉狭窄所致非致残性卒中患者发生缺血性卒中的一项重要外科手术。该手术存在显著的死亡和卒中风险,一些人主张,颈动脉内膜切除术应仅在少数指定的区域中心进行,以取得良好的手术效果。仅靠区域中心能否应对越来越多需要进行颈动脉内膜切除术的患者令人怀疑,因此,地区综合医院的血管外科医生也需要开展该手术。对手术结果进行审核以确保取得可比的疗效很重要。我们介绍了自1981年以来我们在颈动脉内膜切除术方面的经验审核情况。一位对颈动脉手术有特殊兴趣的外科医生连续进行了149例颈动脉内膜切除术。结果与ECST相当,重度(即70 - 99%)同侧颈动脉狭窄患者的30天死亡率为0%,30天总体卒中率为5.7%(严重卒中)。我们已经表明,经过适当培训的地区综合医院外科医生能够安全地进行颈动脉内膜切除术,并取得良好效果。