Jensen P, Minckler D S, Chandler J W
Arch Ophthalmol. 1977 May;95(5):837-42. doi: 10.1001/archopht.1977.04450050115014.
A 74-year-old woman had a radical anterior segment resection for epithelial ingrowth following cataract extraction. Light microscopy demonstrated the presence of a sheet of cells morphologically similar to conjunctival epithelium covering the superior half of the inner surface of the cornea, iris, and ciliary processes. Electron microscopy revealed that frequent hemidesmosomes and a well-developed basal lamina were consistently present along the base of the ingrowing epithelium. The tissue immediately beneath the ingrowing epithelium, lining the cornea, trabecular meshwork and iris, morphologically resembled the subepithelial zone that has been described along the human skin epidermal-dermal junction. Additionally, focal areas of necrosis were noted in the trabecular meshwork. The major structural alterations induced on the surfaces of intraocular structures by the invading epithelium and the associated necrosis probably are responsible for the glaucoma which occurs with epithelial ingrowth.
一名74岁女性因白内障摘除术后上皮内生接受了前段根治性切除术。光学显微镜检查显示，角膜内表面上半部分、虹膜和睫状体表面覆盖着一层形态上与结膜上皮相似的细胞。电子显微镜检查发现，内生上皮底部始终存在频繁的半桥粒和发育良好的基膜。在内生上皮正下方、覆盖角膜、小梁网和虹膜的组织，在形态上类似于人类皮肤表皮-真皮交界处所描述的上皮下区域。此外，在小梁网中发现了局灶性坏死区域。侵入性上皮及相关坏死对眼内结构表面造成的主要结构改变可能是上皮内生伴发青光眼的原因。
