Kamata S
Division of Head and Neck, Cancer Institute Hospital, Toshima-ku, Tokyo, Japan.
Gan To Kagaku Ryoho. 1996 Feb;23(3):265-70.
In order to remove a tumor radically, it is necessary to resect the tumor en-bloc together with surrounding normal tissues as much as possible. This results in a large tissue defect. Since the head and neck region has important functions for daily life such as respiration, speech, chewing, swallowing, the size of tissue defect directly affects post-operative functions and cosmetic results. Recently, the use of free flaps has made it possible to resect the advanced tumor which had been thought to be inoperable before. The introduction of free flaps has permitted reconstruction of the skull base, the nasopharynx, the mandible and the face. These were impossible to reconstruct with pedicled flaps such as delto-pectoral flap and pectoral major musculo-cutaneous flap. Therefore, the indication of reconstructive surgery has been remarkably enlarged for advanced head and neck cancer. We employed reconstructive surgery using free flaps for head and neck cancer in 1982, and, in August 1994, the number of patients operated on with free flaps reached 1,000. Through our experience of head and neck reconstructive surgery, we can conclude that the use of free flaps for the reconstruction in the head and neck region has permitted enlarging surgical indication for far advanced head and neck cancers. And the free flaps have made it possible to assure oral functions such as speech and chewing after reconstruction of the palate or the mandible. The use of free flaps has also decreased the incidence of postoperative complications such as fistula, infection, etc. It is incontestable that reconstructive surgery is indispensable for the treatment of head and neck cancer.
为了彻底切除肿瘤,尽可能将肿瘤与周围正常组织整块切除是必要的。这会导致较大的组织缺损。由于头颈部区域对日常生活具有呼吸、言语、咀嚼、吞咽等重要功能,组织缺损的大小直接影响术后功能和美容效果。近年来,游离皮瓣的应用使以往被认为无法手术切除的晚期肿瘤得以切除成为可能。游离皮瓣的引入使得颅底、鼻咽、下颌骨及面部的重建成为可能。而这些部位用带蒂皮瓣如三角胸肌皮瓣和胸大肌肌皮瓣是无法重建的。因此,晚期头颈癌的重建手术适应证已显著扩大。我们于1982年开始对头颈癌采用游离皮瓣重建手术,到1994年8月,接受游离皮瓣手术的患者人数达到1000例。通过我们的头颈重建手术经验可以得出结论,在头颈部区域使用游离皮瓣进行重建,扩大了晚期头颈癌的手术适应证。并且游离皮瓣使得在腭部或下颌骨重建后保证言语和咀嚼等口腔功能成为可能。游离皮瓣的使用还降低了术后诸如瘘、感染等并发症的发生率。重建手术对头颈癌的治疗不可或缺,这是无可争议的。