Murakawa K, Izumi R, Noma K, Tashiro C, Minatogawa T, Amatsu M
Department of Anesthesiology, Hyogo College of Medicine, Nishinomiya, Japan.
Jpn J Physiol. 1995;45(5):801-9. doi: 10.2170/jjphysiol.45.801.
This study evaluates the circulatory effects of electrical stimulation of the cervical sympathetic trunks on blood flow in the common carotid artery and facial nerve tissue in dogs. Marked increases in arterial pressure and heart rate were observed due to electrical stimulation of the cervical sympathetic trunks, while blood flow volume in the common carotid artery and in the facial nerve tissue decreased markedly. It was assumed that microcirculation of the facial nerve is definitely impaired by electrical stimulation of the cervical sympathetic trunks, and the tonicity of the sympathetic nervous system appears to be a major factor in changes in the microcirculation of the facial nerve. It is well known that impaired circulation in the nutrient vessels of the facial nerve has an important effect on the pathogenesis of facial palsy. The hypertonicity of the sympathetic nervous system is closely involved in the onset of facial palsy.
本研究评估了电刺激犬颈交感干对颈总动脉血流及面神经组织的循环影响。电刺激颈交感干后,观察到动脉压和心率显著升高,而颈总动脉和面神经组织中的血流量则显著减少。据推测,电刺激颈交感干肯定会损害面神经的微循环,并且交感神经系统的紧张性似乎是面神经微循环变化的主要因素。众所周知,面神经营养血管的循环受损对面瘫的发病机制具有重要影响。交感神经系统的高紧张性与面瘫的发病密切相关。