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[新生儿外科病理学中的大量肺出血]

[Massive pulmonary hemorrhage in surgical pathology of the newborn infant].

作者信息

Iñiguez Iñiguez J, Silva Cuevas A, Guerrero Pérez R, Alemán Velasco P

出版信息

Bol Med Hosp Infant Mex. 1977 May-Jun;34(3):681-92.

PMID:871335
Abstract

Massive pulmonary hemorrhage is a complication which frequently leads to death in newborns with conditions susceptible to surgical treatment. Out of 112 postmortem studies, focal hemorrhage was found in 38 (33.9%) and massive in 34 cases (30.3%). In this series, congenital anomalies were found in digestive tract in 70.5% of the patients. Prematurity andlow weight were not important factors as was hypoxia, which was evident in 70.5% of the cases. Manifestations of respiratory insufficiency, shock, rales in lung fields, bleeding in other places different from the lung, blood leaking through upper respiratory ducts, are all clinical features of diagnostic aid. Disturbances in coagulation tests were detected, the same as drop in figures of hemoglobin, acidosis, hypoxia and hypercapnia. Gram-negative germs, with a predominance of Klebsiella, were isolated in 33 cultures. The radiographic finding with reticulogranular image was unfrequent. Among other precipitating factors of pulmonary hemorrhage, identification was made of the surgical disease by itself, surgical and anesthetic procedures, of ventilatory assistance and therapy with oxygen at high concentration for long periods of time.

摘要

大量肺出血是一种并发症,在易接受手术治疗的新生儿中常导致死亡。在112例尸检研究中,38例(33.9%)发现局灶性出血,34例(30.3%)发现大量出血。在该系列研究中,70.5%的患者存在消化道先天性异常。早产和低体重与缺氧一样并非重要因素,70.5%的病例存在明显缺氧。呼吸功能不全、休克、肺野啰音、肺部以外其他部位出血、上呼吸道渗血等表现均为辅助诊断的临床特征。检测到凝血试验异常,同时血红蛋白值下降、酸中毒、缺氧和高碳酸血症。33份培养物中分离出革兰氏阴性菌,以克雷伯菌为主。网状颗粒状影像的影像学表现并不常见。在肺出血的其他促发因素中,明确了手术疾病本身、手术和麻醉操作、通气支持以及长时间高浓度吸氧治疗等因素。

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