Shubitidze A E, Maruashvili I A, Gabisoniia T G, Pkhakadze T Ia
G.G. Eliava Industrial Amalgamation BACTERIOPHAGE, Tbilis.
Antibiot Khimioter. 1995 Aug;40(8):23-7.
Seven hundred and six clinical strains of Staphylococcus spp. isolated in different cities of the former USSR in 1986-1992 were investigated. It was shown that the isolates had multiple drug resistance. The hospital strains of Staphylococcus aureus more frequently contained the plasmids with the molecular weight of 21.0 and 18.0 MD as well as the plasmids with the molecular weight of 1.4 MD determining erythromycin resistance. The plasmids with the molecular weight of 3.0 and 2.6 MD were detected which determined streptomycin and tetracycline resistance respectively. Lincomycin and carbenicillin resistance was determined by the chromosomal genes. The elimination studies demonstrated that gentamicin resistance could be determined by the extrachromosomal genes.
对1986 - 1992年在前苏联不同城市分离出的706株葡萄球菌临床菌株进行了研究。结果表明,这些分离株具有多重耐药性。金黄色葡萄球菌的医院菌株更频繁地含有分子量为21.0和18.0 MD的质粒以及决定红霉素耐药性的分子量为1.4 MD的质粒。检测到分子量分别为3.0和2.6 MD的质粒,它们分别决定链霉素和四环素耐药性。林可霉素和羧苄青霉素耐药性由染色体基因决定。消除研究表明庆大霉素耐药性可由染色体外基因决定。