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[不动杆菌菌株的生物学特性及抗生素敏感性]

[Biological characteristics and antibiotic sensitivity of Acinetobacter strains].

作者信息

Maruashvili I A, Shubitidze A E, Gabisoniia T G, Pkhakadze T Ia, Rekhviashvili N V

机构信息

G.G. Eliava Industrial Amalgamation Bacteriofage, Tbilisi.

出版信息

Antibiot Khimioter. 1995 Aug;40(8):28-31.

PMID:8713434
Abstract

Fifty Acinetobacter strains were investigated. Their differentiation according to the species position showed that 30 strains belonged to A. calcoaceticus and 20 strains belonged to A. lwoffi. It was found that the Acinetobacter strains had multiple drug resistance. They showed 100 per cent resistance to ampicillin, carbenicillin, erythromycin, methicillin, oxacillin, tetracycline, oleandomycin, streptomycin, rondomycin and lincomycin. According to the results of the study the most efficient antibiotics were cefazolin, cefotaxime, ceftazidime and polymyxin. The Acinetobacter hospital strains contained conjugative plasmids of different incompatibility groups. 50 per cent of the Acinetobacter strains contained conjugative R plasmids determining the resistance to streptomycin, kanamycin and tetracycline and referring to the T, J, M and N incompatibility groups. Their molecular weights were 42.0, 35.0, 30.0 and 50.0 MD respectively.

摘要

对50株不动杆菌菌株进行了研究。根据菌种定位进行的区分显示,30株属于醋酸钙不动杆菌,20株属于洛菲不动杆菌。研究发现不动杆菌菌株具有多重耐药性。它们对氨苄西林、羧苄西林、红霉素、甲氧西林、苯唑西林、四环素、竹桃霉素、链霉素、柱晶白霉素和林可霉素呈现100%的耐药性。根据研究结果,最有效的抗生素是头孢唑林、头孢噻肟、头孢他啶和多粘菌素。医院分离的不动杆菌菌株含有不同不相容群的接合质粒。50%的不动杆菌菌株含有决定对链霉素、卡那霉素和四环素耐药性的接合R质粒,属于T、J、M和N不相容群。它们的分子量分别为42.0、35.0、30.0和50.0 MD。

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