正常个体及慢性淋巴细胞白血病患者淋巴细胞中的腺苷脱氨酶（ADA）活性
Adenosine deaminase (ADA) activity in lymphocytes of normal individuals and patients with chronic lymphatic leukaemia.
作者信息
Ramot B, Brok-Simoni F, Barnea N, Bank I, Holtzmann F
出版信息
Br J Haematol. 1977 May;36(1):67-70. doi: 10.1111/j.1365-2141.1977.tb05756.x.
Abstract
Adenosine deaminase (adenosine aminophydrolase, ADA) activity was found to be low in lymphocytes of chronic lymphatic leukaemia (CLL) patients compared to normal lymphocytes. This was determined on 42 controls and 49 CLL patients. The mean activity in normal lymphocytes was found to be 4.35 +/- 3.34 mumol/h/10(8) cells while in CLL cells it was 2.45 +/- 2.54 mumol/h/10(8) cells.
摘要
与正常淋巴细胞相比，慢性淋巴细胞白血病（CLL）患者淋巴细胞中的腺苷脱氨酶（腺苷氨基水解酶，ADA）活性较低。这一结论是在42名对照者和49名CLL患者中得出的。正常淋巴细胞中的平均活性为4.35±3.34微摩尔/小时/10⁸个细胞，而CLL细胞中的平均活性为2.45±2.54微摩尔/小时/10⁸个细胞。
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