Easty D, Dallas N, O'Malley R
Br J Ophthalmol. 1977 May;61(5):321-6. doi: 10.1136/bjo.61.5.321.
Fluorescein angiography of the iris was performed on patients with plastic lens implants with cystoid oedema of the macula, and the nature of the vascular changes was compared with controls provided by patients who did not have macular disease. Densitometry was used to quantitate leakage of fluorescein dye into the anterior chamber in residual angiograms 5 minutes after injection. Cystoid oedema was associated with marked increase in vascular permeability of the iris in the patients with implants, and in aphakics without implants, but to a lesser degree. Although it cannot be concluded that implants themselves cause either the increase in permeability or the onset of macular oedema, the presence of such implants must be considered an additional hazard in an eye which is already at risk. Iris angiography can be used as a diagnostic aid in patients in whom macular oedema is suspected. A persistent increase in permeability associated with a reduction in visual acuity should act as a warning of further visual loss and of eventual cystoid macular degeneration.
对患有黄斑囊样水肿的人工晶状体植入患者进行虹膜荧光血管造影，并将血管变化的性质与无黄斑疾病患者作为对照进行比较。注射后5分钟，使用光密度计对残留血管造影片中荧光素染料向前房的渗漏进行定量。囊样水肿与植入患者以及无植入的无晶状体眼患者虹膜血管通透性的显著增加有关，但程度较轻。虽然不能得出植入物本身会导致通透性增加或黄斑水肿的发生，但在已经处于风险中的眼睛中，此类植入物的存在必须被视为一种额外的危险因素。虹膜血管造影可作为疑似黄斑水肿患者的诊断辅助手段。与视力下降相关的通透性持续增加应作为进一步视力丧失和最终黄斑囊样变性的警告。
