正常和缺氧视网膜组织的血管形成特性。
Vasoformative properties of normal and hypoxic retinal tissue.
作者信息
Kissun R D, Garner A
出版信息
Br J Ophthalmol. 1977 Jun;61(6):394-8. doi: 10.1136/bjo.61.6.394.
Abstract
By cannulating the stroma of rabbit corneae, and introducing extracts of retina and vitreous from newborn kittens subjected to vaso-obliterative doses of oxygen, an attempt was made to test the hypothesis that ischaemic retinal tissue releases a factor with vasoformative properties. It was found that, although retino-vitreal extracts from the test animals elicited a positive response in just over half the experiments, the degree of corneal vascularisation provoked by extracts from intact control animals was only marginally less. Consequently our findings do not permit any definite answer regarding the existence of a specific factor responsible for the proliferation of new vessels on the retinal surface in states associated with retinal hypoxia.
摘要
通过对兔角膜基质进行插管，并引入接受血管闭塞性氧剂量的新生小猫的视网膜和玻璃体提取物，试图检验以下假设：缺血性视网膜组织会释放具有血管形成特性的因子。结果发现，虽然在略多于一半的实验中，试验动物的视网膜玻璃体提取物引发了阳性反应，但完整对照动物的提取物所引起的角膜血管化程度仅略低。因此，我们的研究结果无法就与视网膜缺氧相关状态下视网膜表面新血管增殖的特定因子是否存在给出明确答案。
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本文引用的文献
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Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasia.氧气对发育中的视网膜血管的影响，尤其涉及晶状体后纤维增生问题。
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