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A new approach to the problem of retinal neovascularization.

作者信息

Patz A, Brem S, Finkelstein D, Chen C H, Lutty G, Bennett A, Coughlin W R, Gardner J

出版信息

Ophthalmology. 1978 Jun;85(6):626-37. doi: 10.1016/s0161-6420(78)35640-2.

DOI:10.1016/s0161-6420(78)35640-2
PMID:580956
Abstract

Tumor cells introduced into the rabbit vitreous produced a form of retinal neovascularization, but only when the tumor cells were in direct contact with the vascularized retina. This contrasted with the production of neovascularization at a distance of several millimeters in other angiogenesis models. An extract of adult rabbit vitreous was found to inhibit the growth of limbal neovascularization induced by tumors implanted in the rabbit corneal stroma. The experimental model of retrolental fibroplasia provides a bioassay to investigate further the apparent inhibitory substances in the vitreous.

摘要

相似文献

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A new approach to the problem of retinal neovascularization.
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引用本文的文献

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2
Angiogenesis inhibitors and their delivery systems.
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An approach to the management of neovascularization of the iris and secondary glaucoma.虹膜新生血管化及继发性青光眼的治疗方法。
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Control of tumor growth in animals by infusion of an angiogenesis inhibitor.通过输注血管生成抑制剂来控制动物体内肿瘤的生长。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4331-5. doi: 10.1073/pnas.77.7.4331.
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Neovascularization and tumor growth in the rabbit brain. A model for experimental studies of angiogenesis and the blood-brain barrier.兔脑内的新生血管形成与肿瘤生长。一种用于血管生成和血脑屏障实验研究的模型。
Am J Pathol. 1988 May;131(2):361-72.
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Characterization and quantification of copper sulfate-induced vascularization of the rabbit cornea.硫酸铜诱导兔角膜血管化的表征与定量分析
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Neovascularisation again.又是新生血管形成。
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