Interrelation between plasma magnesium and 25 hydroxy-vitamin D3 levels in chronic renal failure.

In a series of 18 patients suffering from varying degrees of chronic renal failure treated by diet alone, there was a statistically significant positive correlation between plasma magnesium levels and plasms 25 hydroxycholecalciferol (25 HCC) levels. This is thought to be due either to the direct action of 25 HCC on the bone liberating magnesium from bone crystal, or to an increased intestinal absorption of magnesium caused by 25 HCC.