[Effect of submaximal muscular exercise of short duration on urinary excretion of catecholamines, DOPA and their metabolites].

Thirteen human subjects were submitted to a moderate muscular work on ergometric bicycle (at intensity corresponding to 80% of maximal oxygen uptake during 10 min). No modifications were observed in the urinary amounts of the three catecholamines (A, NA, DA), DOPA, DOPAC and 3-MT. On the contrary, the excretion of metadrenaline (MN) and normetadrenaline (NMN) was slightly increased, showing a mild stimulation of adrenergic system. Our result point out the interest of urinary methoxyamines as useful index of adrenergic activity in man. For experimental and physiopathological use, the metabolic alteration induced by a short submaximal muscular work is negligible for most adrenergic compounds, except for MN and NMN, the amounts of which are slightly modified.