Klein R, Klein B E, Lee K E, Moss S E, Cruickshanks K J
Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison 53705-2397, USA.
Diabetes Care. 1996 Feb;19(2):135-41. doi: 10.2337/diacare.19.2.135.
The purpose of this report is to examine the prevalence of erectile dysfunction and relationships to other characteristics in men with younger-onset diabetes.
In a population-based cohort study in southern Wisconsin, prevalence of erectile dysfunction was measured based on self reports in men who were 21 years of age or older, were < 30 years of age at diagnosis of diabetes, had 10 or more years of diabetes, and were taking insulin (n = 365).
Of the study group, 20% reported a history of erectile dysfunction. The prevalence of erectile dysfunction increased with increasing age (from 1.1% in those 21-30 years of age to 47.1% in those 43 years of age or older, P for trend < 0.0001) and with increasing duration of diabetes (P for trend < 0.0001). Erectile dysfunction was associated with presence of severe diabetic retinopathy, a history of peripheral neuropathy, amputation, cardiovascular disease, a higher glycosylated hemoglobin, use of antihypertensive medications, and higher BMI.
These data suggest that tighter glycemic control and careful selection of antihypertensive medications might prove beneficial.
本报告旨在研究早发型糖尿病男性勃起功能障碍的患病率及其与其他特征的关系。
在威斯康星州南部的一项基于人群的队列研究中,根据21岁及以上、糖尿病诊断时年龄小于30岁、患糖尿病10年或更长时间且正在接受胰岛素治疗的男性的自我报告来测量勃起功能障碍的患病率(n = 365)。
在研究组中,20%的人报告有勃起功能障碍病史。勃起功能障碍的患病率随年龄增长而增加(从21 - 30岁人群中的1.1%增至43岁及以上人群中的47.1%,趋势P < 0.0001),且随糖尿病病程延长而增加(趋势P < 0.0001)。勃起功能障碍与严重糖尿病视网膜病变、周围神经病变病史、截肢、心血管疾病、较高的糖化血红蛋白、使用抗高血压药物以及较高的体重指数相关。
这些数据表明,更严格的血糖控制和谨慎选择抗高血压药物可能有益。