Palahniuk R J, Cumming M
Can Anaesth Soc J. 1977 May;24(3):361-70. doi: 10.1007/BF03005109.
Six pregnant sheep were chronically prepared with indwelling catheters in maternal and foetal vessels and a flow probe around a maternal uterine artery. They were anaesthetized the following day with thiopentone and nitrous oxide (70 per cent)--oxygen (30 per cent) maintenance with tracheal intubation. Maternal uterine blood flow fell about 20 per cent following induction of anaesthesia. This resulted from uterine vasoconstriction which, in turn, probably resulted from maternal catecholamine release during light anaesthesia. The foetus in utero developed a mixed metabolic and respiratory acidosis and a fall in oxygen saturation. The possibility that light maternal anaesthesia increases rather than decreases neonatal depression is discussed.
六只怀孕的绵羊长期在母体和胎儿血管中留置导管，并在母体子宫动脉周围放置流量探头。第二天，它们用硫喷妥钠和一氧化二氮（70%）-氧气（30%）进行麻醉，并通过气管插管维持。麻醉诱导后，母体子宫血流量下降了约20%。这是由子宫血管收缩引起的，而子宫血管收缩反过来可能是由于轻度麻醉期间母体儿茶酚胺释放所致。子宫内的胎儿出现了混合性代谢性和呼吸性酸中毒以及氧饱和度下降。本文讨论了轻度母体麻醉增加而非减少新生儿抑制的可能性。
