Brandt B R, Rosén I
Center of Child and Youth Habilitation, Malmöhus County council, Lund, Sweden.
Neuropediatrics. 1995 Dec;26(6):310-2. doi: 10.1055/s-2007-979780.
Sensory neurography of the median nerve was performed bilaterally in 6 children with Down syndrome (DS) aged 11-16 years and in 10 healthy controls of similar age. The sensory nerve conduction velocities from the thumbs and 3rd fingers were recorded and were significantly subnormal in the DS group. Sensory nerve action potentials were also lower in the DS children and the difference was particularly evident following stimuli of the thumbs. Using scalp electrodes sensory evoked potential latencies were recorded in five of the DS children and all controls. There was no obvious difference between the subjects with DS and the controls. It is suggested that an impaired peripheral somatosensory function should be added to previously known symptoms constituting DS. The results may contribute to previous findings of a poor performance of DS children in tests of tactual perception.
对6名年龄在11至16岁的唐氏综合征（DS）患儿和10名年龄相仿的健康对照者进行了双侧正中神经感觉神经成像。记录了拇指和第三指的感觉神经传导速度，DS组明显低于正常水平。DS患儿的感觉神经动作电位也较低，在刺激拇指后差异尤为明显。使用头皮电极记录了5名DS患儿和所有对照者的感觉诱发电位潜伏期。DS患儿与对照者之间没有明显差异。研究表明，外周躯体感觉功能受损应被纳入构成DS的先前已知症状中。这些结果可能有助于解释先前关于DS患儿在触觉感知测试中表现不佳的发现。
