日本鸡群中甲型流感病毒抗体的分布情况。

Distribution of antibodies to influenza A virus in chickens in Japan.

作者信息

Otsuki K, Yoneda H, Iritani Y

机构信息

Department of Veterinary Public Health, Tottori University, Japan.

出版信息

J Vet Med Sci. 1995 Dec;57(6):1063-6. doi: 10.1292/jvms.57.1063.

DOI:10.1292/jvms.57.1063

PMID:8720048

Abstract

A serological surveillance was carried out to detect antibody against influenza A virus in chicken sera. A total of 8,850 field samples were collected from 47 prefectures in Japan. Initially, all the sera were screened by agar gel immunodiffusion and those sera showing positive reaction were investigated for haemagglutination-inhibition (HI) and neuraminidase-inhibition antibodies against influenza viruses. Only 6 samples had antibodies; 4 sera had antibodies against human subtype H1N1 virus; with HI activity against strain A/PR/34; three sera had strong HI activity to strain A/Tottori/4/87, which by haemagglutination test is closely related to A/Yamagata/120/86. The remaining two chicken sera had antibodies against avian subtypes H10N4 and H3N6 viruses respectively.

摘要

开展了一项血清学监测，以检测鸡血清中抗甲型流感病毒的抗体。从日本47个县共采集了8850份现场样本。最初，所有血清均通过琼脂凝胶免疫扩散进行筛查，对呈阳性反应的血清进行了针对流感病毒的血凝抑制（HI）和神经氨酸酶抑制抗体检测。只有6份样本有抗体；4份血清有抗人H1N1亚型病毒的抗体，对A/PR/34毒株有HI活性；3份血清对A/鸟取/4/87毒株有强HI活性，通过血凝试验，该毒株与A/山形/120/86密切相关。其余两份鸡血清分别有抗禽H10N4和H3N6亚型病毒的抗体。