Yamauchi T, Shibata K, Uchiyama S, Osawa M, Iwata M
Department of Neurology, Tokyo Women's Medical College, Japan.
Rinsho Shinkeigaku. 1995 Nov;35(11):1256-8.
We reported a case of cerebral infarction in a young adult following an abuse of cocaine and other drugs. A 27-year-old male was admitted to our hospital because of the abrupt onset of right hemiplegia and dysarthria. Brain CT and MRI examinations showed cerebral infarction in the region of the left caudate head and the left corona radiata. Cerebral angiography revealed total occlusion at the origin of the left middle cerebral artery, with neither vascular malformation nor atherosclerotic change. There were no obvious causes that might lead to cerebral infarction in young adults, including potential cardiac sources of embolism, abnormalities of blood coagulation, or collagen vascular diseases. From his history we learned he had started abusing cocaine and other drugs at the age of 16 years, and that he had been addicted to these drugs up to at least 2 months earlier than the onset of cerebral infarction, so we suggested his drug abuse might have affected the occurrence of cerebral infarction. We would like to emphasize that using 'drugs' should be taken into consideration as a possible cause of cerebral infarction in young adults.
我们报告了一例年轻成年人在滥用可卡因及其他毒品后发生脑梗死的病例。一名27岁男性因突然出现右侧偏瘫和构音障碍入院。脑部CT和MRI检查显示左侧尾状核头部及左侧放射冠区域存在脑梗死。脑血管造影显示左大脑中动脉起始处完全闭塞,未见血管畸形或动脉粥样硬化改变。在年轻成年人中,不存在可能导致脑梗死的明显病因,包括潜在的心脏栓子来源、凝血异常或胶原血管疾病。从他的病史中我们了解到,他16岁开始滥用可卡因及其他毒品,并且在脑梗死发病前至少2个月一直沉迷于这些毒品,因此我们认为他的药物滥用可能影响了脑梗死的发生。我们想强调,对于年轻成年人发生脑梗死,应考虑“药物”使用是一个可能的病因。