[Biocompatibility and extracorporeal circulation].

Present knowledge about biocompatibility during extracorporeal circulation, especially in hemodialysis, has been reported. Clinical implications of membrane biocompatibility on coagulation, fibrinolysis, complement and kalikrein cascade has been analyzed. Particular attention is for the platelet activation in hemodialysis and ist effect upon the coagulation system and dialytic efficiency. The the role of epoprostenol sodium salt (prostacyclin) continous infusion in hemodialysis has been described. Finally future perspectives of anticoagulation during dialytic treatment have been advanced.