Lo J W, Fung C H, Yonan T N, Martinez N
Cancer. 1977 Jun;39(6):2470-4. doi: 10.1002/1097-0142(197706)39:6<2470::aid-cncr2820390625>3.0.co;2-2.
A case of cystadenoma of the pancreas was studied at the light (LM) and the ultrastructural (EM) levels. The observation made under LM that the flattened epithelial cells lining the cystic spaces were similar to the centroacinar cells of a normal pancreas was supported by EM findings. Numerous glycogen granules were demonstrated in the cells, a feature characteristic of fetal but not adult centroacinar cells. A few epithelial cells contained occasional membrane bound dense granules of unknown nature. This observation and the finding of normally appearing islets of Langerhans raise the possibility that this may be an example of a mixed insular-duct cystadenoma. However, if the islets of Langerhans were considered entrapped structures, this tumor should be labelled as a simple serous cystadenoma.
对一例胰腺囊腺瘤进行了光镜（LM）和超微结构（EM）水平的研究。光镜观察发现，囊性腔隙内衬的扁平上皮细胞与正常胰腺的腺泡中心细胞相似，这一观察结果得到了超微结构研究结果的支持。细胞内可见大量糖原颗粒，这是胎儿而非成人腺泡中心细胞的特征。少数上皮细胞偶尔含有性质不明的膜结合致密颗粒。这一观察结果以及出现正常的胰岛，提示这可能是一例混合性胰岛-导管囊腺瘤。然而，如果将胰岛视为包埋结构，则该肿瘤应归类为单纯性浆液性囊腺瘤。
