Black S S, Austin F W, McKinley E
Diagnostic Laboratory Services, College of Veterinary Medicine, Mississippi State University, Mississippi State 39762, USA.
J Wildl Dis. 1996 Apr;32(2):362-6. doi: 10.7589/0090-3558-32.2.362.
In February 1993, clinical, pathological, and microbiological investigations were performed on an adult female gray fox (Urocyon cinereoargenteus) from northern Mississippi (USA). The fox had clinical signs consistent with canine distemper virus encephalitis. Eosinophilic inclusions characteristic of canine distemper virus were in the nuclei and cytoplasm of cerebral neurons and glial cells and in the cytoplasm of urinary, gastric, pancreatic and biliary epithelial cells. The liver contained multifocal microscopic nodular foci of granulomatous to pyogranulomatous inflammation and necrosis with large colonies of small Gram-negative coccobacilli. A low number of small Gram-positive bacilli were within viable-appearing Kupffer cells and hepatocytes. Yersinia pseudotuberculosis and Listeria monocytogenes serotype 4 were isolated from the liver and a mesenteric lymph node.
1993年2月，对一只来自美国密西西比州北部的成年雌性灰狐（赤狐）进行了临床、病理和微生物学调查。这只狐狸有与犬瘟热病毒脑炎相符的临床症状。犬瘟热病毒特有的嗜酸性包涵体存在于脑神经元和神经胶质细胞的细胞核及细胞质中，以及泌尿、胃、胰腺和胆管上皮细胞的细胞质中。肝脏有多处显微镜下可见的肉芽肿性至脓性肉芽肿性炎症和坏死的结节病灶，伴有大量小的革兰氏阴性球杆菌菌落。在外观正常的库普弗细胞和肝细胞内有少量小的革兰氏阳性杆菌。从肝脏和一个肠系膜淋巴结中分离出了假结核耶尔森菌和4型单核细胞增生李斯特菌。
