甲型禽流感病毒血凝素H2在适应新宿主过程中形态、生物学和抗原特性的变化
Changes of morphological, biological and antigenic properties of avian influenza A virus haemagglutinin H2 in the course of adaptation to new host.
作者信息
Lipatov A S, Gitelman A K, Govorkova E A
机构信息
D.I. Ivanovsky Institute of Virology, Russian Academy of Medical Sciences, Moscow, Russia.
出版信息
Acta Virol. 1995 Dec;39(5-6):279-81.
PMID:8722298
Abstract
The alterations of avian influenza A virus haemagglutinin (HA) H2 as a result of adaptation to mice were first investigated in this study. HA of mouse-adapted (MA) variant was somewhat different from that of the original strain in electrophoretical mobility, antigenic structure and in haemagglutination activity with mouse red blood cells.
摘要
本研究首次对甲型禽流感病毒血凝素（HA）H2在适应小鼠过程中的变化进行了调查。适应小鼠的（MA）变异株的HA在电泳迁移率、抗原结构以及与小鼠红细胞的血凝活性方面与原始毒株有所不同。
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