O'Leary D S, Andreason N C, Hurtig R R, Hichwa R D, Watkins G L, Ponto L L, Rogers M, Kirchner P T
Department of Psychiatry, University of Iowa Hospitals and Clinics, Iowa City 52242-1057, USA.
Brain Lang. 1996 Apr;53(1):20-39. doi: 10.1006/brln.1996.0034.
Regional cerebral blood flow (rCBF) was measured using positron emission tomography with oxygen- 15 labeled water as 10 normal subjects listened to three types of auditory stimuli (environmental sounds, meaningless speech, and words) presented binaurally or dichotically. Binaurally presented environmental sounds and words caused similar bilateral rCBF increases in left and right superior temporal gyri. Dichotically presented stimuli (subjects attended to left or right ears) caused asymmetric activation in the temporal lobes, resulting from increased rCBF in temporal lobe regions contralateral to the attended ear and decreased rCBF in the opposite hemisphere. The results indicate that auditorily presented language and non-language stimuli activate similar temporal regions, that dichotic stimulation dramatically changes rCBF in temporal lobes, and that the change is due both to attentional mechanisms and to hemispheric specialization.
对10名正常受试者进行正电子发射断层扫描，以15O标记水测量局部脑血流量（rCBF），受试者双耳或两耳分别聆听三种类型的听觉刺激（环境声音、无意义言语和单词）。双耳呈现的环境声音和单词会使左右颞上回的双侧rCBF出现类似增加。两耳分别呈现刺激（受试者关注左耳或右耳）会导致颞叶不对称激活，这是由于受试耳对侧颞叶区域的rCBF增加以及对侧半球的rCBF减少所致。结果表明，听觉呈现的语言和非语言刺激会激活相似的颞叶区域，两耳分别刺激会显著改变颞叶的rCBF，且这种变化既归因于注意力机制，也归因于半球特化。
