[Changes in binding parameters of fluorescent probes 1-anilinonaphthalene-8-sulfonate and 4-(n-dimethylaminostyryl)-1-methylpyridinium n-toluolsulfonate with liposomes upon radiation exposure].

Using fluorescent probes 1-anilinonaphthalene-8-sulfonate and 4-(n-dimethylaminostyryl)-1-methylpyridinium n-toluenesulfonate the effect of radiation on the properties of liposomes composed of phosphatidylcholine and diphosphatidylglycerol has been investigated. Parameters of the probes association with liposomes were estimated. It was suggested that radiation-induced increase of 1-anilinonaphthalene-8-sulfonate fluorescence intensity and decrease of that for 4-(n-dimethylaminostyryl)-1-methylpyridinium n-toluenesulfonate are caused by lipid's peroxidation.