Zato M A, Matilla A, Gomez T, Jimenez V
Department of Ophthalmology, Centro Médico La Zarzuela, Madrid, Spain.
Ophthalmic Surg Lasers. 1996 May;27(5 Suppl):S466-70.
Numerous modifications have been proposed to photorefractive keratectomy (PRK) in the treatment of myopia in excess of 6.00 diopters (D). One of the techniques employed in an attempt to achieve better refractive results and to avoid, above all, the appearance of an intense haze, is the technique known as multizone.
We have attempted, in a prospective study, to compare the refractive results and the complications of monozone and multizone techniques for the treatment of moderate and high myopia. We performed 139 monozone PRKs and 30 multizone PRKs with a one-year follow-up.
We did not find statistically significant differences between the two groups either in the degree of correction obtained nor in the final visual acuity. A statistically significant difference was found only in the number of cases with severe haze (greater than 3) which proved more frequent in the monozone group.
Our results suggest the techniques are comparable in predictability and effectiveness. However, the incidence of severe haze was lower in the multizone group, which may render its use preferable in the treatment of myopias in excess of 6.00 D.
为治疗超过6.00屈光度（D）的近视，人们已对准分子激光角膜切削术（PRK）提出了多种改进方法。为了获得更好的屈光效果，尤其是避免出现严重的角膜 haze，其中一种采用的技术是多区技术。
在一项前瞻性研究中，我们试图比较单区和多区技术治疗中度和高度近视的屈光效果及并发症。我们进行了139例单区PRK和30例多区PRK，并随访一年。
两组在获得的矫正度数或最终视力方面均未发现统计学上的显著差异。仅在严重 haze（大于3级）病例数上发现有统计学显著差异，单区组更为常见。
我们的结果表明，两种技术在可预测性和有效性方面具有可比性。然而，多区组严重 haze 的发生率较低，这可能使其在治疗超过6.00 D的近视时更具优势。
