Simpson E, McAllister E J, Hainsworth I R
Clin Chim Acta. 1977 Jun 15;77(3):415-22. doi: 10.1016/0009-8981(77)90248-0.
Human placenta has been recommended as the source of the alkaline phosphatase used for the preparation of control or reference materials. The effect of certain inhibitors, which may be present in the reagents, on control materials containing the placental isoenzyme, is shown to differ significantly from their effect on the isoenzymes in patient's sera. This finding indicates that if control materials are used which contain only human placental alkaline phosphatase, changes in accuracy resulting from differences in reagent quality may be missed, or alternatively a change in accuracy may be indicated by the quality control results which does not apply to the patient's sera.
人胎盘已被推荐作为制备对照或参考物质所用碱性磷酸酶的来源。结果表明，试剂中可能存在的某些抑制剂对含胎盘同工酶的对照物质的作用，与它们对患者血清中同工酶的作用有显著差异。这一发现表明，如果使用仅含人胎盘碱性磷酸酶的对照物质，可能会遗漏因试剂质量差异导致的准确性变化，或者质量控制结果可能显示准确性发生了变化，但这并不适用于患者血清。
