Quinn M J, Thompson J E, Crotty K, McCarthy W H, Coates A S
Sydney Melanoma Unit, Royal Prince Alfred Hospital, New South Wales, Australia.
J Hand Surg Am. 1996 May;21(3):506-11. doi: 10.1016/S0363-5023(96)80371-6.
Subungual melanoma is a rare but well-recognized tumor of the hand. Its management is ill defined and the factors influencing prognosis have not been well described. The clinicopathologic features of a series of 38 patients with subungual melanoma of the hand are reported. The median thickness was 3 mm, and only seven patients presented with pathologic stage I disease (American Joint Committee on Cancer [AJCC] system). Ulceration and lack of pigmentation were the only significant univariate prognostic indicators. There was no significant difference in local recurrence rates among patients whose amputation was carried out proximal or distal to the interphalangeal joint of the thumb or the middle of the middle phalanx in the other fingers. Management of the regional lymph node field based on the use of selective lymphadenectomy is described.
甲下黑色素瘤是一种罕见但已被充分认识的手部肿瘤。其治疗方法尚不明确，影响预后的因素也未得到充分描述。本文报告了一组38例手部甲下黑色素瘤患者的临床病理特征。肿瘤厚度中位数为3毫米，仅有7例患者表现为病理I期疾病（美国癌症联合委员会[AJCC]系统）。溃疡和无色素沉着是仅有的显著单因素预后指标。在拇指指间关节近端或其他手指中节指骨中部近端或远端进行截肢的患者，局部复发率无显著差异。本文还描述了基于选择性淋巴结清扫术的区域淋巴结处理方法。
