Metzner W
Department of Zoology, University of Munich, Germany.
J Comp Neurol. 1996 Apr 29;368(2):252-69. doi: 10.1002/(SICI)1096-9861(19960429)368:2<252::AID-CNE6>3.0.CO;2-2.
Neurophysiological recordings suggest that audio-vocal neurons located in the paralemniscal tegmentum of the midbrain in horseshoe bats provide an interface between the pathways for auditory sensory processing and those for the motor control of vocalization. To verify these physiological results anatomically, the projection pattern of the audio-vocally active area in the paralemniscal tegmentum was investigated by using extracellular tracer injections of wheat germ agglutinin conjugated to horseradish peroxidase. Several nuclei of the lemniscal auditory pathway (dorsal nucleus of the lateral lemniscus, central nucleus of the inferior colliculus, lateral superior olive) as well as the nucleus of the central acoustic tract appear to project to the paralemniscal tegmentum. Other possible sources of afferent projections are a small but distinctly labeled structure within the lateral hypothalamic area, the substantia nigra pars compacta, the deep mesencephalic nucleus, the rostral portion of the inferior colliculus, the deep and intermediate layers of the superior colliculus, and several small areas in the rhombencephalic reticular formation. No direct efferent projection from the audio-vocally active area of the paralemniscal tegmentum to primarily auditory structures was found. Instead, the main targets were structures that are involved in the control of different motor patterns. These targets include the deep and intermediate layers of the superior colliculus and the dorsomedial portion of the facial nucleus, both of which most probably control pinna movements in cats, and the reticular formation medial and caudal to the facial nucleus and rostral to the nucleus ambiguus, which represents an area involved in the control of vocalization. Hence, the anatomical projection pattern suggests that the paralemniscal tegmentum in horseshoe bats serves as a link between the processing of auditory information and the control of vocalization and related motor patterns.
神经生理学记录表明，位于马蹄蝠中脑旁臂被盖区的听觉-发声神经元在听觉感觉处理通路和发声运动控制通路之间提供了一个接口。为了从解剖学上验证这些生理学结果，通过使用与辣根过氧化物酶结合的小麦胚芽凝集素进行细胞外示踪剂注射，研究了旁臂被盖区听觉-发声活跃区域的投射模式。lemniscal听觉通路的几个核团（外侧丘系背核、下丘中央核、外侧上橄榄核）以及中央听道核似乎投射到旁臂被盖区。传入投射的其他可能来源是下丘脑外侧区内一个小但标记明显的结构、黑质致密部、中脑深部核、下丘的前部、上丘的深层和中间层以及后脑网状结构中的几个小区域。未发现旁臂被盖区听觉-发声活跃区域向主要听觉结构的直接传出投射。相反，主要目标是参与不同运动模式控制的结构。这些目标包括上丘的深层和中间层以及面神经核的背内侧部分，这两者很可能控制猫的耳廓运动，以及面神经核内侧和尾侧以及疑核头侧的网状结构，这代表了一个参与发声控制的区域。因此，解剖学投射模式表明，马蹄蝠的旁臂被盖区充当了听觉信息处理与发声及相关运动模式控制之间的联系。
