Arnar D O, Danielsen R
Department of Medicine, Landspítalinn, University Hospital, Reykjavík, Iceland.
Cardiology. 1996 May-Jun;87(3):181-8. doi: 10.1159/000177084.
A prospective study was conducted to evaluate how many patients maintain normal sinus rhythm after direct current (DC) cardioversion of atrial arrhythmias and to assess factors predictive of long-term success. The study group consisted of 61 patients (45 men) aged 18-88 years (mean age 66 +/- 11 years) who underwent cardioversion at our department from October 1990 to June 1992. Prior to cardioversion, the patients' medical history, medications, heart size on chest X ray, and echocardiographic findings were reviewed. Overall, 41 (67.2%) patients were in atrial fibrillation, while 20 (32.8%) had atrial flutter. Only 15% of the patients had valvular heart disease. Sinus rhythm was restored by DC cardioversion in 47 (77%) patients, none of whom experienced an embolic event prior to discharge. Patients with atrial flutter had a higher conversion rate (95%) than those in atrial fibrillation (68.3%; p = 0.024), and also patients with an arrhythmia for less than 1 week (94.4%) compared to those with a longer or unknown duration (69.8%; p = 0.047). The primary success rate was not influenced by heart size on chest X ray or echocardiographic variables. The study protocol aimed at following up the patients for 1 year after cardioversion. Of the 47 patients who converted to sinus rhythm data are available on 44 for a mean follow-up of 11 +/- 3 months (range 1-14 months), at which time 25 (57%) still remained in sinus rhythm. Heart size on the chest X ray was significantly increased in the group that did not maintain sinus rhythm (p = 0.03) and their left atrial size on echocardiography was slightly increased (p = 0.10). Patients who originally had atrial flutter were more likely to remain in sinus rhythm than those who had been in atrial fibrillation (p = 0.12), as did patients with an arrhythmia for less than 1 week prior to cardioversion in comparison to those with a longer or unknown duration (p = 0.11). Thus, in contrast to previous reports, according to these recent data on a patient population with a low prevalence of valvular heart disease, DC cardioversion can be attempted in most patients with atrial tachyarrhythmias. Clinical factors, heart size on chest X ray and echocardiographic findings should, however, be considered before deciding to perform DC cardioversion.
进行了一项前瞻性研究,以评估心房心律失常直流电(DC)复律后有多少患者维持正常窦性心律,并评估预测长期成功的因素。研究组由1990年10月至1992年6月在我科接受复律的61例患者(45例男性)组成,年龄在18 - 88岁(平均年龄66±11岁)。在复律前,回顾了患者的病史、用药情况、胸部X线检查的心脏大小以及超声心动图检查结果。总体而言,41例(67.2%)患者为房颤,20例(32.8%)为房扑。仅15%的患者患有瓣膜性心脏病。47例(77%)患者通过DC复律恢复了窦性心律,其中无一例在出院前发生栓塞事件。房扑患者的复律率(95%)高于房颤患者(68.3%;p = 0.024),心律失常持续时间少于1周的患者(94.4%)也高于持续时间较长或不明的患者(69.8%;p = 0.047)。主要成功率不受胸部X线检查的心脏大小或超声心动图变量的影响。研究方案旨在对患者在复律后进行1年的随访。在47例恢复窦性心律的患者中,44例有随访数据,平均随访时间为11±3个月(范围1 - 14个月),此时25例(57%)仍维持窦性心律。未维持窦性心律的患者胸部X线检查的心脏大小显著增加(p = 0.03),其超声心动图检查的左心房大小略有增加(p = 0.10)。最初为房扑的患者比房颤患者更有可能维持窦性心律(p = 0.12),复律前心律失常持续时间少于1周的患者与持续时间较长或不明的患者相比也是如此(p = 0.11)。因此,与先前的报告相反,根据这些关于瓣膜性心脏病患病率较低的患者群体的最新数据,大多数房性快速心律失常患者可尝试进行DC复律。然而,在决定进行DC复律之前,应考虑临床因素、胸部X线检查的心脏大小和超声心动图检查结果。