Eichenbaum H
Center for Behavioral Neuroscience, State University of New York at Stony Brook, 11794-2575, USA.
Curr Opin Neurobiol. 1996 Apr;6(2):187-95. doi: 10.1016/s0959-4388(96)80072-9.
The prominent view that the rodent hippocampus is dedicated to spatial memory has been challenged recently by observations that both limit the nature of hippocampal spatial representation and extend its scope beyond literal space. These findings reveal that the rodent hippocampus mediates memory representations on the basis of non-spatial, as well as spatial, relations among items in memory, and supports access to these memories in a variety of situations. Therefore, the defining features of hippocampal representation in rodents, as in humans, lie not in the modality of the information processed, but in the organization of the information that supports a capacity for flexible memory expression.
啮齿动物海马体专门负责空间记忆这一主流观点,最近受到了一些观察结果的挑战,这些观察结果既限制了海马体空间表征的性质,又将其范围扩展到了字面意义上的空间之外。这些发现表明,啮齿动物海马体在记忆中基于非空间以及空间关系来介导记忆表征,并在各种情况下支持对这些记忆的提取。因此,与人类一样,啮齿动物海马体表征的决定性特征不在于所处理信息的模态,而在于支持灵活记忆表达能力的信息组织方式。