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[抑郁症中皮质过程的紊乱组织]

[The disordered organization of the cortical processes in depression].

作者信息

Strelets V B, Ivanitskiĭ A M, Ivanitskiĭ G A, Artseulova O K, Novototskiĭ-Vlasov V Iu, Golikova Zh V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1996 Mar-Apr;46(2):274-81.

PMID:8726560
Abstract

The study of depressive patients with the method of the EEG mapping revealed some stable differences from the norm. Firstly, in depression there are the disturbances of the definite cortical zones' activation: the right anterior and the left posterior cortical parts are hyperactivated while the left anterior and the right posterior-- relatively inhibited, evidently causing the informational processing disturbances. The important link of these disturbances--the disconnection of the anterior and the posterior cortical regions that could be called "transversal functional blockade". The second feature of the electrical activity of the brain in depression is the absence of the high frequency component of alpha-rhythm, that evidently in normal conditions is connected with the positive emotions mechanisms. The third feature is the difference in arousal reaction in the alpha- and beta-bands frequencies.

摘要

采用脑电地形图方法对抑郁症患者进行的研究揭示了一些与正常情况的稳定差异。首先,在抑郁症中存在特定皮质区域激活的紊乱:右侧前部和左侧后部皮质部分过度激活,而左侧前部和右侧后部相对受抑制,这显然导致了信息处理紊乱。这些紊乱的重要环节——前后皮质区域的断开连接,可称为“横向功能阻断”。抑郁症患者脑电活动的第二个特征是缺乏α波节律的高频成分,这在正常情况下显然与积极情绪机制有关。第三个特征是α波和β波频段的唤醒反应存在差异。

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引用本文的文献

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Impaired functional connectivity at EEG alpha and theta frequency bands in major depression.重度抑郁症患者脑电图α和θ频段功能连接受损。
Hum Brain Mapp. 2007 Mar;28(3):247-61. doi: 10.1002/hbm.20275.