Benbadis S R
Department of Neurology, Medical College of Wisconsin, Milwaukee 53226, USA.
Pharmacotherapy. 1996 May-Jun;16(3):463-5.
A 64-year-old man with narcolepsy could not take stimulant drugs due to coronary heart disease. In the past he noted improvement in alertness when taking codeine for pain, but this was eventually discontinued. After he developed end-stage renal disease, and because the use of stimulants in this setting may be difficult, treatment with codeine was again initiated. This resulted in dramatic improvement in alertness and substantial reduction of cataplexy. Because it is simple to use and familiar to most physicians, codeine may be the drug of choice for narcoleptic patients who are undergoing hemodialysis.
一名患有发作性睡病的64岁男性因冠心病无法服用兴奋剂药物。过去，他在服用可待因止痛时注意到警觉性有所改善，但最终停止了使用。在他发展为终末期肾病后，由于在这种情况下使用兴奋剂可能存在困难，于是再次开始使用可待因进行治疗。这导致警觉性显著改善，猝倒症状大幅减轻。由于可待因使用简便且大多数医生都熟悉，它可能是正在接受血液透析的发作性睡病患者的首选药物。
