Tajima S, Inazumi T, Kobayashi T
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
Dermatology. 1996;192(3):264-8. doi: 10.1159/000246381.
We report a case of acrogeria. Biochemical analysis of patient fibroblasts demonstrated unaltered type III collagen synthesis. An RNA hybridization assay demonstrated that the levels of type I and elastin mRNAs were normal. The patient had multiple yellow papules on the neck, axilla and inguinal area which clinically and histologically resembled late-onset focal dermal elastosis. Both diseases may have some similar abnormal metabolism of connective tissue.
