Katz S E, Rootman J
Department of Ophthalmology, Vancouver Hospital, University of British Columbia, Canada.
Ophthalmic Plast Reconstr Surg. 1996 Jun;12(2):121-6. doi: 10.1097/00002341-199606000-00006.
The goal of this article is to establish the incidence and scope of adverse reactions to bone wax in a large orbital surgical series. We report two patients with bone wax granulomas of the orbit as a remote surgical complication. These are the first reported cases of adverse reactions to bone wax in the ophthalmic literature. A chart review was conducted on all patients from the University of British Columbia Orbit Clinic that had surgery with temporary or permanent removal of orbital bone. Two patients with bone wax granulomas were identified. In one case, intraoperative cultures grew Staphylococcus aureus, confirming that the wax may indeed act as a nidus for infection. No cases of pseudoarthrosis have occurred. This syndrome of chronic granulomatous giant cell foreign body inflammation has characteristic clinical, radiologic, and histopathologic features. The literature regarding adverse reactions to bone wax is reviewed, and specific implications for orbital surgery are discussed.
本文的目的是确定在一个大型眼眶手术系列中骨蜡不良反应的发生率和范围。我们报告了2例眼眶骨蜡肉芽肿患者，这是一种远期手术并发症。这些是眼科文献中首次报道的骨蜡不良反应病例。对英属哥伦比亚大学眼眶诊所所有进行了临时性或永久性眼眶骨切除手术的患者进行了病历回顾。确定了2例骨蜡肉芽肿患者。在1例病例中，术中培养出金黄色葡萄球菌，证实骨蜡确实可能成为感染灶。未发生假关节病例。这种慢性肉芽肿性巨细胞异物炎症综合征具有特征性的临床、放射学和组织病理学特征。本文回顾了有关骨蜡不良反应的文献，并讨论了其对眼眶手术的具体影响。
