细菌转铁蛋白和乳铁蛋白受体。
Bacterial transferrin and lactoferrin receptors.
作者信息
Gray-Owen S D, Schryvers A B
机构信息
Dept of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary, Alberta, Canada.
出版信息
Trends Microbiol. 1996 May;4(5):185-91. doi: 10.1016/0966-842x(96)10025-1.
PMID:8727598
Abstract
Pathogenic members of the Neisseriaceae and Pasteurellaceae express outer-membrane receptor proteins involved in the direct assimilation of iron from the host glycoproteins transferrin and lactoferrin. The critical requirement of iron for growth suggests that this function is an important component of colonization and infection. A model describing this novel process is presented.
摘要
奈瑟菌科和巴斯德菌科的致病成员表达外膜受体蛋白，这些蛋白参与从宿主糖蛋白转铁蛋白和乳铁蛋白中直接摄取铁。铁对生长的关键需求表明，这一功能是定植和感染的重要组成部分。本文提出了一个描述这一新过程的模型。
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