Harada A, Nonami T, Nakao A, Kurokawa T, Takagi H
Department of Surgery II, Nagoya University School of Medicine, Japan.
Semin Surg Oncol. 1996 May-Jun;12(3):193-6. doi: 10.1002/(SICI)1098-2388(199605/06)12:3<193::AID-SSU9>3.0.CO;2-2.
Preventing a rupture of esophagogastric varices (EGV) is very important in aggressively treating hepatocellular carcinoma (HCC) in cirrhotic patients. We therefore performed simultaneous partial hepatic resection and direct interruption procedure on nine patients with HCC and concomitant EGV. Patients were selected on the basis of their stages of HCC and hepatic functional reserve. Postoperative hospital courses of all patients were uneventful. Six patients had recurrence of HCC and received non-surgical anti-tumor treatments. Only one patient had upper gastrointestinal bleeding at 18 months after operation, and the other eight patients have had no episodes of upper gastrointestinal bleeding during the follow-up period. The 5-year survival rate of these patients was 48%. This operative procedure is quite effective and is one of the treatments of choice for patients with less advanced HCC and concomitant risk of EGV.
在积极治疗肝硬化患者的肝细胞癌（HCC）时，预防食管胃静脉曲张（EGV）破裂非常重要。因此，我们对9例HCC合并EGV患者实施了同期部分肝切除及直接阻断术。根据患者的HCC分期和肝功能储备情况进行患者选择。所有患者术后住院过程均顺利。6例患者出现HCC复发并接受了非手术抗肿瘤治疗。仅1例患者在术后18个月发生上消化道出血，其他8例患者在随访期间未发生上消化道出血。这些患者的5年生存率为48%。该手术方法相当有效，是治疗病情不太严重的HCC合并EGV风险患者的首选治疗方法之一。
