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临床实践中的造血生长因子

Hematopoietic growth factors in clinical practice.

作者信息

Pitler L R

机构信息

AIDS Clinical Trials Unit/Section of Infectious Disease, Rush Presbyterian-St. Luke's Medical Center, Chicago, IL, USA.

出版信息

Semin Oncol Nurs. 1996 May;12(2):115-29. doi: 10.1016/s0749-2081(96)80006-4.

DOI:10.1016/s0749-2081(96)80006-4
PMID:8727799
Abstract

OBJECTIVE

To review the hematopoietic growth factors (HGFs) as they relate to hematopoiesis, dosing, administration, toxicities and clinical indications.

DATA SOURCES

Research studies, abstracts, review articles, product package inserts, and book chapters pertaining to HGFs.

CONCLUSIONS

HGFs are essential components for the development of blood cells. Recombinant DNA technology and the availability of HGFs have significantly altered the care of patients with cancer and bone marrow disorders.

IMPLICATIONS FOR NURSING PRACTICE

Nurses can play a major role in assisting patients, families, and various consumers by providing education about HGFs as well as their indications, schedule, methods of administration, and toxicities. Familiarity with the HGFs and the literature available can assist nurses in developing management strategies for patients receiving these agents.

摘要

目的

综述造血生长因子(HGFs),涉及其与造血作用、剂量、给药方式、毒性及临床适应证的关系。

数据来源

与造血生长因子相关的研究、摘要、综述文章、产品包装说明书及书籍章节。

结论

造血生长因子是血细胞发育的重要组成部分。重组DNA技术及造血生长因子的可得性显著改变了癌症及骨髓疾病患者的护理。

对护理实践的启示

护士在协助患者、家属及各类消费者方面可发挥重要作用,提供有关造血生长因子及其适应证、给药时间表、给药方法和毒性的教育。熟悉造血生长因子及现有文献可帮助护士为接受这些药物的患者制定管理策略。

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