拉扎罗类化合物可抑制人类中性粒细胞的NADPH氧化酶活性。 - Suppr

Human neutrophil NADPH-oxidase activity is inhibited by lazaroids.

作者信息

Theron A J, Anderson R

机构信息

Medical Research Council Unit for Inflammation and Immunity, Department of Immunology, University of Pretoria, South Africa.

出版信息

Inflammation. 1996 Apr;20(2):139-50. doi: 10.1007/BF01487401.

DOI:10.1007/BF01487401

PMID:8728017

Abstract

摘要

相似文献

Human neutrophil NADPH-oxidase activity is inhibited by lazaroids.拉扎罗类化合物可抑制人类中性粒细胞的NADPH氧化酶活性。

Inflammation. 1996 Apr;20(2):139-50. doi: 10.1007/BF01487401.

Inhibition of superoxide-generating NADPH oxidase of human neutrophils by lazaroids (21-aminosteroids and 2-methylaminochromans).

Biochem Pharmacol. 1993 Jan 7;45(1):241-51. doi: 10.1016/0006-2952(93)90398-g.

An in vitro EPR study of the free-radical scavenging actions of the lazaroid antioxidants U-74500A and U-78517F.拉扎罗类抗氧化剂U-74500A和U-78517F自由基清除作用的体外电子顺磁共振研究

Free Radic Biol Med. 1995 Jul;19(1):21-30. doi: 10.1016/0891-5849(95)00007-k.

NADPH-oxidase activity of stimulated neutrophils is markedly increased by serum.受刺激的中性粒细胞的NADPH氧化酶活性会因血清而显著增加。

Inflammation. 1994 Oct;18(5):459-67. doi: 10.1007/BF01560693.

Antioxidant lazaroids enhance differentiation of C2 skeletal muscle cells.

Neurosci Lett. 1995 Feb 17;186(2-3):177-80. doi: 10.1016/0304-3940(95)11283-3.

Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism.血根碱是通过非氧化还原机制对二甲基亚砜诱导分化的HL-60细胞中氧化爆发的有效抑制剂。

Chem Biol Interact. 2004 Jan 15;147(1):35-47. doi: 10.1016/j.cbi.2003.10.003.

Effects of tocopherols and 2,2'-carboxyethyl hydroxychromans on phorbol-ester-stimulated neutrophils.生育酚和2,2'-羧乙基羟基苯并二氢吡喃对佛波酯刺激的中性粒细胞的影响。

J Nutr Biochem. 2008 May;19(5):320-7. doi: 10.1016/j.jnutbio.2007.05.002. Epub 2007 Aug 1.

Phosphatidic acid induces the respiratory burst of electropermeabilized human neutrophils by acting on a downstream step of protein kinase C.

FEBS Lett. 1993 Aug 9;328(1-2):67-70. doi: 10.1016/0014-5793(93)80967-y.

Priming by grepafloxacin on respiratory burst of human neutrophils: its possible mechanism.格帕沙星对人中性粒细胞呼吸爆发的启动作用：其可能机制。

J Antimicrob Chemother. 2002 Oct;50(4):469-78. doi: 10.1093/jac/dkf160.

Cyclic AMP inhibits the respiratory burst of electropermeabilized human neutrophils at a downstream site of protein kinase C.环磷酸腺苷在蛋白激酶C的下游位点抑制电通透处理的人中性粒细胞的呼吸爆发。

Biochim Biophys Acta. 1993 Jun 6;1177(2):167-73. doi: 10.1016/0167-4889(93)90036-o.

本文引用的文献

Inhibition of superoxide-generating NADPH oxidase of human neutrophils by lazaroids (21-aminosteroids and 2-methylaminochromans).

Biochem Pharmacol. 1993 Jan 7;45(1):241-51. doi: 10.1016/0006-2952(93)90398-g.

The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils.人中性粒细胞中组装好的NADPH氧化酶激活对磷脂酶A2的需求。

Biochem J. 1994 Jan 1;297 ( Pt 1)(Pt 1):217-23. doi: 10.1042/bj2970217.

NADPH-oxidase activity of stimulated neutrophils is markedly increased by serum.受刺激的中性粒细胞的NADPH氧化酶活性会因血清而显著增加。

Inflammation. 1994 Oct;18(5):459-67. doi: 10.1007/BF01560693.

Arachidonic acid increases the activity of the assembled NADPH oxidase in cytoplasmic membranes and endosomes.花生四烯酸可增强细胞质膜和内体中组装好的NADPH氧化酶的活性。

Biochim Biophys Acta. 1993 Mar 10;1176(1-2):51-8. doi: 10.1016/0167-4889(93)90176-p.

Lucigenin-dependent chemiluminescence as a new assay for NAD(P)H-oxidase activity in particulate fractions of human polymorphonuclear leukocytes.基于光泽精的化学发光法作为检测人多形核白细胞微粒体组分中NAD(P)H氧化酶活性的新方法。

J Immunol Methods. 1984 Jun 8;71(1):61-7. doi: 10.1016/0022-1759(84)90206-0.

Oxidants from phagocytes: agents of defense and destruction.吞噬细胞产生的氧化剂：防御与破坏的媒介

Blood. 1984 Nov;64(5):959-66.

Leukotriene B4 mobilizes calcium without the breakdown of polyphosphoinositides and the production of phosphatidic acid in rabbit neutrophils.白三烯B4在兔中性粒细胞中可动员钙离子，而不伴有多磷酸肌醇的分解及磷脂酸的生成。

Proc Natl Acad Sci U S A. 1984 Oct;81(19):5966-9. doi: 10.1073/pnas.81.19.5966.

Determination of ATP and ADP in blood platelets: a modification of the firefly luciferase assay for plasma.血小板中ATP和ADP的测定：血浆萤火虫荧光素酶测定法的一种改进

Anal Biochem. 1972 Apr;46(2):489-501. doi: 10.1016/0003-2697(72)90323-5.

Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality.白细胞计数对冠心病、癌症及全因死亡率的预后重要性。

JAMA. 1985 Oct 11;254(14):1932-7.

Phagocytes as carcinogens: malignant transformation produced by human neutrophils.作为致癌物的吞噬细胞：人类中性粒细胞引发的恶性转化

Science. 1985 Mar 8;227(4691):1231-3. doi: 10.1126/science.3975611.

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Human neutrophil NADPH-oxidase activity is inhibited by lazaroids.

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