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正常受试者睡眠期间自发脑磁图活动及听觉诱发电位的源估计

Source estimation of spontaneous MEG activity and auditory evoked responses in normal subjects during sleep.

作者信息

Iramina K, Ueno S

机构信息

Department of Computer Sciences and Communication Engineering, Kyushu University, Fukuoka, Japan.

出版信息

Brain Topogr. 1996 Spring;8(3):297-301. doi: 10.1007/BF01184788.

DOI:10.1007/BF01184788
PMID:8728422
Abstract

This study focuses on source estimation of spontaneous MEG activity and auditory evoked responses during sleep. Sources of K-complexes and auditory evoked responses were investigated by magnetoencephalograph (MEG) and electroencephalograph (EEG) measurements, simultaneously. Sources of K-complexes during stage 2 sleep were investigated. The MEG results suggested that the sources of K-complexes can be modeled by two current dipoles. Dipoles for the K-complexes were estimated to be located 5 mm away from the sources of the N100 components of auditory evoked responses during wakefulness. Sources of auditory evoked responses during each sleep stage were also investigated to clarify the origins of the K-complex, the vertex sharp transient, and delta waves. Estimated dipoles for the N100 component for each sleep stage were estimated to be at slightly different locations in the auditory area. Based upon results of the MEG measurements and the EEG topographies, sources of the N330 component can be modeled by multiple current dipoles, which are seen to be distributed diffusely throughout the cerebral cortex.

摘要

本研究聚焦于睡眠期间自发脑磁图(MEG)活动及听觉诱发反应的源估计。通过同时进行脑磁图(MEG)和脑电图(EEG)测量,研究了K复合波和听觉诱发反应的源。对睡眠二期期间K复合波的源进行了研究。脑磁图结果表明,K复合波的源可用两个电流偶极进行建模。估计K复合波的偶极位于清醒时听觉诱发反应N100成分源的5毫米处。还对每个睡眠阶段听觉诱发反应的源进行了研究,以阐明K复合波、头顶尖波和δ波的起源。估计每个睡眠阶段N100成分的偶极在听觉区域的位置略有不同。基于脑磁图测量结果和脑电图地形图,N330成分的源可用多个电流偶极进行建模,这些偶极在整个大脑皮层呈弥散分布。

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