Jones D T, Thornton J M
Department of Biological Sciences, University of Warwick, Coventry, UK.
Curr Opin Struct Biol. 1996 Apr;6(2):210-6. doi: 10.1016/s0959-440x(96)80076-5.
Despite little progress in ab initio solutions to the problem of predicting a protein's tertiary structure, over the past four years or so the development of fold-recognition methods for tertiary structure prediction has been the source of some encouragement in this difficult field. Despite promising initial results, these methods are clearly not yet fully mature and many groups are now working on different aspects of the methods involved in the hope of increasing the reliability and sensitivity of these tools.
尽管在从头预测蛋白质三级结构问题的解决方案方面进展甚微，但在过去四年左右的时间里，用于三级结构预测的折叠识别方法的发展，在这个困难的领域中带来了一些鼓舞。尽管取得了令人鼓舞的初步成果，但这些方法显然尚未完全成熟，许多研究小组目前正在研究这些方法的不同方面，希望提高这些工具的可靠性和灵敏度。
