Vera J A, Argüello B, Crisosto C A
Clínica de Diagnóstico Ginecoobstétrico-Clindigo.
Rev Chil Obstet Ginecol. 1995;60(3):195-8.
In order to assess the relationship between echographic endometrial thickness and pattern and the probability of clinical pregnancy and delivery we analyzed retrospectively 51 cycles of IFV-ET. Patients were classified in three categories of endometrial thickness: < 9 mm, 9.1-11 mm and > 11 mm and in two types of endometrial pattern: type 1 (non triple line) or type 2 (triple line). The average endometrial thickness of patients who got pregnant and those who did not was 11.8 +/- 1.8 mm and 10.6 +/- 1.7 mm respectively (p = NS). There were no clinical pregnancies in patients with endometrial thickness < 9 mm (p < 0.01). The average endometrial thickness in patients with endometrial pattern type 1 and type 2 was 11.1 +/- 1.2 mm and 10.9 +/- 1.9 mm respectively (p = NS). Patients who presented type 2 endometrial pattern (n = 39) produced eleven clinical pregnancies (28.2%) and those with type 1 (n = 2) only one clinical pregnancy (8.3%), which ended in spontaneous abortion (p < 0.01). When both variables, thickness and pattern, were considered together, patients with endometrial pattern type 2 and thickness > 11 mm had a probability of clinical pregnancy and of delivery of 43.8% and 25%, respectively, who is statistically significant (p < 0.03). We conclude that endometrial thickness and pattern, taken together, offer a valuable prognostic value for the outcome of an IVF-ET cycle.
为了评估超声检查的子宫内膜厚度和类型与临床妊娠及分娩概率之间的关系,我们回顾性分析了51个体外受精-胚胎移植(IVF-ET)周期。患者根据子宫内膜厚度分为三类:<9mm、9.1 - 11mm和>11mm,根据子宫内膜类型分为两种:1型(非三线型)或2型(三线型)。怀孕患者和未怀孕患者的平均子宫内膜厚度分别为11.8±1.8mm和10.6±1.7mm(p=无统计学意义)。子宫内膜厚度<9mm的患者未发生临床妊娠(p<0.01)。1型和2型子宫内膜患者的平均子宫内膜厚度分别为11.1±1.2mm和10.9±1.9mm(p=无统计学意义)。呈现2型子宫内膜类型的患者(n=39)有11例临床妊娠(28.2%),而1型患者(n=2)只有1例临床妊娠(8.3%),该例以自然流产告终(p<0.01)。当同时考虑厚度和类型这两个变量时,2型子宫内膜且厚度>11mm的患者临床妊娠和分娩的概率分别为43.8%和25%,具有统计学意义(p<0.03)。我们得出结论,子宫内膜厚度和类型综合起来可为IVF-ET周期的结局提供有价值的预后评估。