（D-蛋氨酸2，脯氨酸5）脑啡肽酰胺：一种强效的类吗啡镇痛药。 - Suppr

Suppr

超能文献

(D-met2, pro5)-enkephalinamide: a potent morphine-like analgesic.

作者信息

Székely J I, Rónai A Z, Dunai-Kovács Z, Miglécz E, Berzétri I, Bajusz S, Gráf L

出版信息

Eur J Pharmacol. 1977 Jun 1;43(3):293-4. doi: 10.1016/0014-2999(77)90032-2.

DOI:10.1016/0014-2999(77)90032-2

PMID:872884

Abstract

摘要

相似文献

(D-met2, pro5)-enkephalinamide: a potent morphine-like analgesic.（D-蛋氨酸2，脯氨酸5）脑啡肽酰胺：一种强效的类吗啡镇痛药。

Eur J Pharmacol. 1977 Jun 1;43(3):293-4. doi: 10.1016/0014-2999(77)90032-2.

Comparison of tolerance development and dependence capacities of morphine, beta-endorphin, and [D-Met2, Pro5]-enkephalinamide.吗啡、β-内啡肽和[D-蛋氨酸2，脯氨酸5]-脑啡肽酰胺耐受性发展和依赖性产生能力的比较。

Psychopharmacology (Berl). 1979 Mar 29;62(1):29-34. doi: 10.1007/BF00426031.

Action of enkephalin analogues and morphine on brain acetylcholine release: differential reversal by naloxone and an opiate pentapeptide.脑啡肽类似物和吗啡对脑乙酰胆碱释放的作用：纳洛酮和一种阿片五肽的不同逆转作用

Br J Pharmacol. 1980;71(1):201-10. doi: 10.1111/j.1476-5381.1980.tb10927.x.

Prolactin and growth hormone releasing activity of [D-Met2, Pro5]-enkephalinamide in the rat after systemic administration.[D-蛋氨酸2，脯氨酸5]-脑啡肽酰胺全身给药后对大鼠催乳素和生长激素释放活性的影响

Experientia. 1978 Dec 15;34(12):1650-1. doi: 10.1007/BF02034731.

Biphasic effects of a potent enkephalin analogue (D-Met2,Pro5)-enkephalinamide and morphine on locomotor activity in mice.

Psychopharmacology (Berl). 1980;71(3):299-301. doi: 10.1007/BF00433065.

Antinociceptive activity of glycosidic enkephalin analogues.糖苷化脑啡肽类似物的抗伤害感受活性。

Psychopharmacology (Berl). 1990;101(2):222-5. doi: 10.1007/BF02244130.

In vivo antagonism by naloxone of morphine, beta-endorphin and a synthetic enkephalin analog.

J Pharmacol Exp Ther. 1978 Dec;207(3):878-83.

Species differences in the relative analgesic potencies of some classical opiates and opioid peptides.

Psychopharmacology (Berl). 1984;82(4):400-2. doi: 10.1007/BF00427694.

Morphine and [D-Met2,Pro5]enkephalinamide do not show specific neuroleptic activity.

Eur J Pharmacol. 1982 Jun 4;80(4):359-68. doi: 10.1016/0014-2999(82)90081-4.

Analgesic effects of intraventricular morphine and enkephalins in nondependent and morphine-dependent rats.脑室内注射吗啡和脑啡肽对非成瘾和吗啡成瘾大鼠的镇痛作用。

J Pharmacol Exp Ther. 1982 Jul;222(1):190-7.

引用本文的文献

Integrating deep learning and molecular dynamics simulations for FXR antagonist discovery.整合深度学习与分子动力学模拟以发现法尼醇X受体拮抗剂

Mol Divers. 2025 Apr 2. doi: 10.1007/s11030-025-11145-2.

Impact of non-proteinogenic amino acids in the discovery and development of peptide therapeutics.非蛋白氨基酸在肽类治疗药物的发现和开发中的影响。

Amino Acids. 2020 Sep;52(9):1207-1226. doi: 10.1007/s00726-020-02890-9. Epub 2020 Sep 18.

Super-active enkephalin analogues. Simple tripeptide hydroxyalkylamides exhibit surprisingly high and long-lasting opioid activities.超活性脑啡肽类似物。简单的三肽羟烷基酰胺表现出惊人的高且持久的阿片样活性。

Naturwissenschaften. 1981 Apr;68(4):210-2. doi: 10.1007/BF01047210.

Biphasic effects of a potent enkephalin analogue (D-Met2,Pro5)-enkephalinamide and morphine on locomotor activity in mice.

Psychopharmacology (Berl). 1980;71(3):299-301. doi: 10.1007/BF00433065.

Opiates modulate insulin action in vivo in dogs.阿片类药物在体内对犬的胰岛素作用产生调节。

Diabetologia. 1984 Jan;26(1):65-9. doi: 10.1007/BF00252266.

Evidence that the contractile response of the guinea-pig ileum to capsaicin is due to release of substance P.豚鼠回肠对辣椒素的收缩反应是由于P物质释放的证据。

J Physiol. 1982 Nov;332:157-67. doi: 10.1113/jphysiol.1982.sp014407.

Effects of changes in the structure of enkephalins and of narcotic analgesic drugs on their interactions with mu- and delta-receptors.脑啡肽结构变化及麻醉性镇痛药对其与μ和δ受体相互作用的影响。

Br J Pharmacol. 1980 Feb;68(2):333-42. doi: 10.1111/j.1476-5381.1980.tb10422.x.

Peripheral effects of opioid drugs on capsaicin-sensitive neurones of the guinea-pig bronchus and rabbit ear.阿片类药物对豚鼠支气管和兔耳辣椒素敏感神经元的外周作用。

Naunyn Schmiedebergs Arch Pharmacol. 1987 Sep;336(3):316-20. doi: 10.1007/BF00172684.

Antinociceptive effects of the novel opioid peptide BW443C compared with classical opiates; peripheral versus central actions.新型阿片肽BW443C与经典阿片类药物相比的抗伤害感受作用；外周与中枢作用

Br J Pharmacol. 1988 Jan;93(1):85-92. doi: 10.1111/j.1476-5381.1988.tb11408.x.

Effects of D-Met2, Pro5-enkephalinamide on pain tolerance and some cognitive functions in man.

Psychopharmacology (Berl). 1986;89(4):409-13. doi: 10.1007/BF02412112.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验