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Membrane-associated and cytoplasmic fatty acid-binding proteins.

作者信息

Van Nieuwenhoven F A, Van der Vusse G J, Glatz J F

机构信息

Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), University of Limburg, The Netherlands.

出版信息

Lipids. 1996 Mar;31 Suppl:S223-7. doi: 10.1007/BF02637080.

DOI:10.1007/BF02637080
PMID:8729123
Abstract

A number of cellular fatty acid-binding proteins are being implicated in the uptake and intracellular transport of long-chain fatty acids by parenchymal cells. Having been a topic of research for more than 20 years, cytoplasmic fatty acid-binding proteins now are assigned various pivotal functions in intracellular fatty acid transport and metabolism. More recently several membrane-associated fatty acid-binding proteins have been identified and these proteins are thought to function in the transmembrane transport of fatty acids. In this review, a short summary is provided of the latest developments in this research area.

摘要

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Phospholipase-A2-dependent signalling in the heart.心脏中磷脂酶 A2 依赖性信号传导
Cardiovasc Res. 1995 Oct;30(4):518-29. doi: 10.1016/0008-6363(95)00098-4.
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从钩虫Ancylostoma ceylanicum 中鉴定出脂肪酸和视黄醇结合蛋白的同系物。
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Genes, diet and type 2 diabetes mellitus: a review.基因、饮食与2型糖尿病:综述
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5
Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin.膜结合蛋白是与白蛋白结合的长链脂肪酸肝细胞跨膜通量的主要决定因素。
Pharm Res. 2005 Nov;22(11):1793-804. doi: 10.1007/s11095-005-7248-2. Epub 2005 Aug 16.
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Structural and functional characterization of the mouse fatty acid translocase promoter: activation during adipose differentiation.小鼠脂肪酸转运蛋白启动子的结构与功能特性:脂肪分化过程中的激活作用
Biochem J. 2001 Dec 1;360(Pt 2):305-12. doi: 10.1042/0264-6021:3600305.
7
A surface-associated retinol- and fatty acid-binding protein (Gp-FAR-1) from the potato cyst nematode Globodera pallida: lipid binding activities, structural analysis and expression pattern.来自马铃薯金线虫球孢囊线虫的一种表面相关视黄醇和脂肪酸结合蛋白(Gp-FAR-1):脂质结合活性、结构分析及表达模式
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Genetic predictors of plasma lipid response to diet intervention.饮食干预后血浆脂质反应的遗传预测指标
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A sensitive immunoassay for rat fatty acid translocase (CD36) using phage antibodies selected on cell transfectants: abundant presence of fatty acid translocase/CD36 in cardiac and red skeletal muscle and up-regulation in diabetes.一种利用在细胞转染体上筛选出的噬菌体抗体对大鼠脂肪酸转运蛋白(CD36)进行的灵敏免疫测定:脂肪酸转运蛋白/CD36在心脏和红色骨骼肌中大量存在以及在糖尿病中上调。
Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):407-14.
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Mol Cell Biochem. 1998 Mar;180(1-2):43-51.
J Biol Chem. 1993 Apr 15;268(11):7885-92.
4
Cytoplasmic fatty acid binding protein: significance for intracellular transport of fatty acids and putative role on signal transduction pathways.细胞质脂肪酸结合蛋白:对脂肪酸细胞内转运的意义及在信号转导途径中的假定作用。
Prostaglandins Leukot Essent Fatty Acids. 1993 Jan;48(1):33-41. doi: 10.1016/0952-3278(93)90007-j.
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Comparison of plasma membrane FABP and mitochondrial isoform of aspartate aminotransferase from rat liver.大鼠肝脏质膜脂肪酸结合蛋白与天冬氨酸氨基转移酶线粒体同工型的比较
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Expression of rat L-FABP in mouse fibroblasts: role in fat absorption.大鼠肝型脂肪酸结合蛋白在小鼠成纤维细胞中的表达:在脂肪吸收中的作用
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Cellular binding proteins for fatty acids and retinoids: similar or specialized functions?脂肪酸和类视黄醇的细胞结合蛋白:功能相似还是具有特异性?
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