Bustamante-Calvillo M E, Damasio-Santana D L, Alvarez-Muñoz M T, Muñoz-Hernandez O
Unidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatriía, México.
Ginecol Obstet Mex. 1996 Mar;64:114-6.
The aim of this study was to determine the prevalence of specific antibodies against rubella virus in pregnant women from Iztapalapa and Nezahualcóyotl areas of the valley of Mexico, in order to evaluate susceptibility to this virus in these areas. Serum samples collected from 5535 women between 15 and 44 years old were studied by the hemaglutination inhibition test. 92.6% of positivity was obtained and no significant difference was observed between different age groups. The prevalence of rubella antibodies in pregnant women was 92.4% for Iztapalapa zone and 92.8% for Nezahualcóyotl. The titles of antibodies against rubella virus more frecuently presented were 1:16 (36.3%) and 1:32 (29.6%). The data obtained in this study suggest that women attending Medical Services of the Mexican Institute of Social Segurity in reproductive age from the Iztapalapa and Nezahualcóyotl areas, do not need massive vaccination against rubella virus.
本研究的目的是确定墨西哥谷伊萨帕拉帕和内萨瓦尔科约特尔地区孕妇中针对风疹病毒的特异性抗体的流行情况,以便评估这些地区对该病毒的易感性。通过血凝抑制试验对从5535名15至44岁女性收集的血清样本进行了研究。获得了92.6%的阳性率,不同年龄组之间未观察到显著差异。伊萨帕拉帕地区孕妇风疹抗体的流行率为92.4%,内萨瓦尔科约特尔地区为92.8%。针对风疹病毒的抗体滴度最常见的是1:16(36.3%)和1:32(29.6%)。本研究获得的数据表明,来自伊萨帕拉帕和内萨瓦尔科约特尔地区育龄期的、前往墨西哥社会保障局医疗服务机构就诊的女性,不需要大规模接种风疹病毒疫苗。