Verstichel P, Berthelot J L, Randriananja H, Crozier S, Masson C
Clinique Neurologique, Hôpital Beaujon, Clichy.
Presse Med. 1996 Feb 17;25(6):230-4.
Cervical spondylotic myelopathy is usually a chronic and progressive disease. In a few cases, however, dramatic tetraplegia sometimes occurs after even minor injury.
We report seven patients (6 males, 1 female, aged from 41 to 63), who suffered from acute myelopathy after an injury.
In 5 cases, the injury revealed the cervical spondylotic myelopathy. A hyperextension of the cervical spine was found in 5 cases. The injury was severe in only one case, but there was no bony abnormalities, except arthrosis. The most common cause was a fall. In contrast, severe tetraplegia was found in 4 cases. Spontaneous, but incomplete, recuperation occurred in 4 patients. In all 7 cases, CT scan and MRI showed congenital cervical stenosis associated with cervical spondylosis. The level of disco-osteophytic changes was mainly in C4, C5, C6. On T2-weighted spin-echo image, an increased signal intensity was present in the cord of 3 patients, but was not correlated with the severity of the symptoms, nor with improvement. Surgical treatment was performed in 6 cases: 3 laminectomies, 3 anterior or antero-lateral approaches. Improvement after operative decompression was observed in all but one case, even when the motor or sensory deficit persists for more than one year. Motricity of the inferior limbs improved better than the other deficits, perhaps because of the location of non-reversible lesions in the spinal gray matter.
The acute medullary syndrome of cervical spondylotic myelopathy is serious and can cause major handicaps. This complication justifies a preventive surgical attitude when medullar signs are moderate, and cervical imagery shows a spondylotic compression of the cord with congenital stenosis.
脊髓型颈椎病通常是一种慢性进行性疾病。然而,在少数情况下,即使是轻微损伤后也可能突然发生严重四肢瘫。
我们报告7例(6例男性,1例女性,年龄41至63岁)受伤后发生急性脊髓病的患者。
5例损伤显示为脊髓型颈椎病。5例发现颈椎过伸。仅1例损伤严重,但除关节病外无骨质异常。最常见的原因是跌倒。相比之下,4例出现严重四肢瘫。4例患者自发但不完全恢复。所有7例患者的CT扫描和MRI均显示先天性颈椎管狭窄合并颈椎病。椎间盘骨赘改变主要位于C4、C5、C6水平。在T2加权自旋回波图像上,3例患者脊髓信号强度增加,但与症状严重程度及恢复情况均无关。6例患者接受了手术治疗:3例行椎板切除术,3例行前路或前外侧入路手术。除1例患者外,所有患者术后减压均有改善,即使运动或感觉功能障碍持续超过1年。下肢运动功能改善优于其他功能障碍,可能是因为脊髓灰质中存在不可逆病变。
脊髓型颈椎病急性脊髓综合征病情严重,可导致严重残疾。当脊髓症状较轻,颈椎影像学显示脊髓有颈椎病性压迫合并先天性狭窄时,这种并发症证明采取预防性手术态度是合理的。