Schlaeppi M, Edwards K, Fuller R W, Sharma R
Glaxo Research and Development, Uxbridge, Middlesex.
Br J Clin Pract. 1996 Jan-Feb;50(1):14-9.
Asthmatic patients who were regular and experienced users of the metered-dose inhaler (MDI) but with no history of powder inhaler use were interviewed by questionnaire. Most (71%) of the 159 adults recruited had suffered from asthma for more than five years; 89% had used an MDI for more than one year. In all, 153 (97%) found their current MDI easy or very easy to handle. Effectiveness in delivering the drug and ease of operation were the two features of the device they were most satisfied with. The two features 'of an ideal inhaler' rated most highly were the presence of a dose counter and ease of use during an attack (58% and 72% of respondents, respectively). Other important features included hygiene, sensation that a dose had been taken, and small size. When attitudes towards the Diskus inhaler and the Turbuhaler inhaler were compared, 108 (68%) would have been quite or very happy to have a Diskus inhaler prescribed for them, and 79 (50%) a Turbuhaler inhaler. The Diskus inhaler scored significantly better than the Turbuhaler inhaler for knowing how many doses were left, the presence of an attached cover, attractiveness (p < 0.001), hygiene, shape, weight (p = 0.001), and perceived ease of use (p = 0.002). The Turbuhaler inhaler scored significantly better in terms of size (p < 0.001). Overall, the Diskus inhaler was preferred by 104 of 159 patients (p < 0.001), with perceived ease of use, the dose counter, and shape cited as the main reasons for preference.
通过问卷调查对那些经常且熟练使用定量吸入器（MDI）但无干粉吸入器使用史的哮喘患者进行了访谈。招募的159名成年人中，大多数（71%）患有哮喘超过五年；89%使用MDI超过一年。总体而言，153名（97%）患者认为他们目前使用的MDI易于或非常易于操作。药物递送效果和操作简便性是他们对该设备最满意的两个特点。被评为“理想吸入器”最高的两个特点是有剂量计数器以及在发作时易于使用（分别有58%和72%的受访者提到）。其他重要特点包括卫生、有已吸入一剂的感觉以及体积小。当比较对都保吸入器和准纳器吸入器的态度时，108名（68%）患者表示如果给自己开都保吸入器会相当满意或非常高兴，79名（50%）患者对准纳器吸入器有同样感受。在知晓剩余剂量数量、有附带的盖子、吸引力（p<0.001）、卫生、形状、重量（p = 0.001）以及感知易用性（p = 0.002）方面，都保吸入器的得分显著高于准纳器吸入器。准纳器吸入器在体积方面得分显著更高（p<0.001）。总体而言，159名患者中有104名更喜欢都保吸入器（p<0.001），感知易用性、剂量计数器和形状被列为偏好的主要原因。
